Oportunidades de Investigación Públicas

22-06-2024 Diseño y configuración de un MVP de un instrumento de microfluidos libre para la generación de gotas.
Ya hemos lanzado un microscopio estroboscópico de microfluidos de fabricación digital (https://wenzel-lab.github.io/strobe-enhanced-microscopy-stage/), pero muchas extensiones se encuentran aún en fase de prototipo (por ejemplo, https://github.com/wenzel-lab/modular-microfluidics-workstation-controller) y necesitan integrarse en un diseño limpio y atractivo que sea adecuado para su uso en un laboratorio de nivel 2 de seguridad biológica. También desarrollamos documentaciones detalladas para la replicación y material de formación para la enseñanza y la investigación.
Prerequisitos:  no tiene.

Tiene un método de evaluación Nota 1-7, con 20 créditos y tiene 1/2 vacantes disponibles

Mentor(es): Ver en la plataforma

Public Research Opportunities

22-06-2024 Design and arrangement of a MVP of an open source microfluidics instrument for pressure driven droplet generation.
We have already released a digitally-fabricated microfluidics strobe microscope (https://wenzel-lab.github.io/strobe-enhanced-microscopy-stage/) but many extensions are still at a prototyping stage (e.g. https://github.com/wenzel-lab/modular-microfluidics-workstation-controller) and need to be integrated into a clean, attractive design that is suitable for the use in a biological safety level 2 laboratory. We also develop detailed documentations for replication, and training material for teaching and research.
Prerequisites:  None.

Evaluation method: Nota 1-7, with 1/2 available vacants

Mentor(s): Open in the plataform
19-12-2022 microfluidic image analysis for single cell or single molecule analysis
Microfluidic singe cell (mother machine) or single molecule analysis (synthetic biology essays in cell-free reaction droplets) are powerful platforms allowing acurate biomedical quantification of pathogenic load and bacteria phenotypes. However, these methods are only available in few leading labs in the worlds. In this project, we will explore the use of the open flexure microscope and potentially 3d printed syringe pumps to open up the workflow for many more users. This requires biological lab work at the IIBM including some software testing and or improvent.
Keywords:       Microfluidos
Prerequisites:  None.

Evaluation method: Nota 1-7, with 0/2 available vacants

Mentor(s): Open in the plataform
11-12-2022 Optimisation of an automated stage to deposit microfluidic droplets for bio applications
Microfluidic droplet sorting allows the experimental handling of millions of molecular biology experiments in one day. To further culture cells in droplets, they need to be collected and individualised, which can be done in a well plate or culture plate. In this project, the aim is to optimise such a droplet deposition system using prototyping methods, examples from the literature and software development in python.
Prerequisites:  None.

Evaluation method: Nota 1-7, with 0/1 available vacants

Mentor(s): Open in the plataform
13-06-2022 Microfluidic droplet experiments for single cell microbial genomics of pathogens
This projects in in the context of an ongoing research collaboration and focuses on experiments using cutting edge microfluidic technology for single cell genomics. This helps us answer important questions about bacterial resistance to antibiotics. Some prior molecular biology or microbiology knowledge (such as how to work with a pipette) is required for the participation in this project.
Prerequisites:  None.

Evaluation method: Nota 1-7, with 0/1 available vacants

Mentor(s): Open in the plataform